Importance of LCMS in Forced Degradation Studies for new Chemical Entities
نویسندگان
چکیده
منابع مشابه
Beyond new chemical entities
Antibody-type agents (i.e., antibodies and derivatives thereof) may be produced as clinically valuable antidotes, which conceivably could be developed in tandem with prospective new pharmaceutical products so as to render the risks of clinical trials more acceptable from a regulatory standpoint. Yet, this is but a relatively narrow view of the full potential utility associated with antibody-typ...
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Forced Degradation Studies of Aloe Emodin and Emodin by HPTLC.
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Amlodipine is a long-acting calcium channel blocker used in the treatment of hypertension and angina pectoris. S-(−)-amlodipine besylate is a safer and longer-acting alternative to the existing racemate [1]. Although several products based on the active enantiomer have reached the market, information on its chemical, physical and thermal stability during storage is lacking [2, 3]. The objective...
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ژورنال
عنوان ژورنال: International Journal of pharma and Bio Sciences
سال: 2021
ISSN: 0975-6299
DOI: 10.22376/ijpbs/lpr.2021.11.1.l188-193